Ganglion cell layer segmentation and the two-flash multifocal electroretinogram improve structure function analysis in early glaucoma
نویسندگان
چکیده
منابع مشابه
The multifocal pattern electroretinogram in glaucoma
BACKGROUND The pattern ERG can be used to detect early glaucomatous change, because the response of cells in the inner retina from (typically) 20 degrees -40 degrees of area is reduced before perimetric abnormality is certain. The multifocal pattern electroretinogram (mfPERG) allows analysis of many local regions within this area. The aim of this study was to investigate whether in patients wit...
متن کاملSlow flash multifocal electroretinogram in myopia
PURPOSE The purpose of this study was to investigate the characteristics of retinal function in myopes using a modified multifocal electroretinogram (mfERG) protocol, the slow flash (sf-mfERG) paradigm, which is thought to primarily reflect responses of ON- and OFF-bipolar cells and emphasize the late response components. METHODS Twenty-eight subjects (10 emmetropes and 18 myopes) underwent m...
متن کاملGlaucoma detection is facilitated by luminance modulation of the global flash multifocal electroretinogram.
PURPOSE To investigate the variation of retinal electrophysiological function in glaucoma by using the global flash multifocal electroretinogram (mfERG) stimulation with altered differences in the stimulus luminance of the multifocal flashes, in an attempt to alter the levels of inner retinal contributions. METHODS The mfERG was assessed with a visual stimulus in steps of four video frames, w...
متن کاملRetinal function in normal and diabetic eyes mapped with the slow flash multifocal electroretinogram.
PURPOSE It has been suggested that late components of the standard multifocal electroretinogram (mfERG) are preferentially affected by diabetes mellitus. The slow-flash (sf-)mfERG stimulates with flashes separated by dark periods, facilitating interpretation of late first-order response components compared with standard multifocal stimulation. Retinal function and response component changes wer...
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Purpose. To compare two different spectral-domain optical coherence tomography (OCT) systems in regard to full macular thickness (MT) and ganglion cell layer-inner plexiform layer (GCIPL) measures and in regard to structure-function correlation when compared to standard automated perimetry (SAP). Methods. Seventeen primary open angle glaucoma patients and 16 controls (one eye per subject) were ...
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ژورنال
عنوان ژورنال: Graefe's Archive for Clinical and Experimental Ophthalmology
سال: 2017
ISSN: 0721-832X,1435-702X
DOI: 10.1007/s00417-017-3722-x